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ALENDRONATE SODIUM

About

ALENDRONATE SODIUM is used to prevent and treat osteoporosis in adults and helps strengthen bones. This medicine also helps to reduce the risk of spine and hip fractures. Osteoporosis is a medical condition in which bone becomes thin or weak. 

ALENDRONATE SODIUM contains 'Alendronate sodium', which comes in the category of drugs known as 'bisphosphonates”, which prevent bone breakdown by slowing bone loss. This helps in keeping the bones strong and increases the thickness of bone, and reduces the risk of broken bones (fractures). It also helps rebuild bones, which reduces the risk of spine and hip fractures.

Your doctor will advise you how often you take ALENDRONATE SODIUM based on your medical condition. It has been reported that some persons experience undesirable effects of name that include stomach pain, constipation, nausea, gas, and diarrhoea. Most of these side effects of ALENDRONATE SODIUM do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

The use of ALENDRONATE SODIUM is restricted in persons who are allergic to any constituent of medication or have problems with the oesophagus or low levels of calcium in the blood. This medicine should not be taken by a person who cannot sit upright or stand for at least half an hour after taking this medicine. This medication can increase the risk of jaw bone problems (osteonecrosis), which is high in persons with pre-existing dental problems or people treated with steroids, cancer, blood cell disorders, or radiation. So, consult with the doctor about the risks associated with ALENDRONATE SODIUM. This medicine is only a part of a complete program of treatment that includes bone mineral density testing, diet changes, exercise, and taking calcium and vitamin supplements, so follow all the directions given by the doctor.

Uses of ALENDRONATE SODIUM

Treatment of Osteoporosis.

Medicinal Benefits

ALENDRONATE SODIUM comes into the category of bisphosphonates, which is prescribed to prevent and treat osteoporosis in persons with weak bones. It prevents the loss of bones that happens after menopause and helps to rebuild bones. ALENDRONATE SODIUM contains Alendronate sodium, which helps to maintain strong bones and reduces the chances of broken bones (fractures). It also increases the thickness of bone and rebuilds bones, which reduces the risk of spine and hip fractures. ALENDRONATE SODIUM is also indicated for the treatment of increasing bone mass in people with osteoporosis, glucocorticoid-induced osteoporosis and Paget's disease of bone.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it. Liquid: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ALENDRONATE SODIUM

  • Stomach pain
  • Constipation
  • Nausea
  • Gas
  • Diarrhoea

In-Depth Precautions and Warning

Drug Warnings

ALENDRONATE SODIUM can increase the risk of jaw bone problems (osteonecrosis), especially in people who are being treated with steroids, chemotherapy, radiation, cancer, blood cell disorders, and pre-existing dental problems. Let your doctor know if you ever had problems with the oesophagus, low blood calcium levels, trouble swallowing, problems with your stomach or digestion, hypocalcaemia, a dental problem (you may need a dental exam before you begin taking alendronate), kidney disease; or any condition that makes it hard for your body to absorb nutrients from food (malabsorption) before taking this medicine. Pregnant and breastfeeding women should consult with their doctor before taking ALENDRONATE SODIUM.

Drug Interactions

Drug-Drug Interactions: ALENDRONATE SODIUM may interact with calcium supplements/antacids and nonsteroidal anti-inflammatory drugs (aspirin, naproxen, diclofenac).

Drug-Food Interactions: Foods like mineral water, coffee, tea, or juice may decrease the absorption of ALENDRONATE SODIUM.

Drug-Disease Interactions: Inform your doctor if you have aspiration, ONJ (Osteonecrosis of the jaw), hypocalcaemia, upper GI mucosal irritation, cardiovascular disease, renal dysfunction and asthma before starting ALENDRONATE SODIUM.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • CALCIUM
  • NAPROXEN
  • DICLOFENAC
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      A person should limit the consumption of alcohol as it can increase the risk of stomach side effects from ALENDRONATE SODIUM. Talk to the doctor, and they will check on the stomach problems.

    • Safety Warning

      Pregnancy

      caution

      It is unknown whether ALENDRONATE SODIUM may harm the baby, so tell your doctor if you are pregnant or planning to be pregnant. It should only be used if the potential benefit justifies the potential risk.

    • Safety Warning

      Breast Feeding

      unsafe

      It isn’t known if ALENDRONATE SODIUM passes into breast milk. If it does, it may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child.

    • Safety Warning

      Driving

      safe if prescribed

      ALENDRONATE SODIUM does not influence a person's ability to drive so one can drive safely.

    • Safety Warning

      Liver

      caution

      ALENDRONATE SODIUM should be taken with caution and should only be suggested by the doctor.

    • Safety Warning

      Kidney

      caution

      Tell your doctor if you have kidney disorders, as after checking the health condition, the doctor will decide whether this medicine is safe to prescribe or not.

    • Safety Warning

      Children

      unsafe

      ALENDRONATE SODIUM should not be given to children or adolescents whose age is less than 18 years.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include dairy products like milk, yoghurt, cheese or milk-based custard in your diet.
    • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
    • Include the best dietary sources of vitamin D, such as fish liver oils and vitamin D–fortified milk.
    • Snack on calcium-rich nuts like Brazil nuts or almonds. 
    • Sprinkle sesame seeds over your food, vegetables and salads. Sesame seeds are high in calcium.
    • Avoid or reduce the intake of caffeine, soft drinks and alcohol that inhibit calcium absorption.
    • Replace the meat with tofu or tempeh for extra calcium in your food.

    Special Advise

    • ​​​​​Certain diagnostic tests like bone density scans should be done regularly to check bone mineral density (BMD) while using ALENDRONATE SODIUM.
    • The intake of ALENDRONATE SODIUM can cause a false bone imaging test result, so if you are taking ALENDRONATE SODIUM, let your doctor know before any bone test.

    Patients Concern

    Disease/Condition Glossary

    Osteoporosis: It is a medical condition that causes thinning and weakening of the bones. The chance of developing osteoporosis increases with age, after menopause, or by taking corticosteroid medications (such as prednisone) for a long period of time. If proper treatment is not provided, then it can even result in broken bones. In the starting days, osteoporosis does not show any symptoms. In osteoporosis, bones can break at any time, even during daily activities like lifting or even during minor activities. Fractures usually occur at the hip, spine, or wrist, which can even lead to stooped posture (‘dowager’s hump’) and loss of movement.

    FAQs

    ALENDRONATE SODIUM is indicated for preventing and treating osteoporosis in adults and helps strengthen bones. This medicine also reduces the risk of spine and hip fractures. Osteoporosis is a medical condition in which bone becomes thin or weak.

    ALENDRONATE SODIUM contains Alendronate sodium, a drug known as bisphosphonates. Bisphosphonates prevent bone breakdown by slowing bone loss. This helps keep bones strong, increases bone thickness, and reduces the risk of broken bones (fractures). It also helps rebuild bones, which reduces the risk of spine and hip fractures.

    A person who is allergic to any component present in ALENDRONATE SODIUM, has a problem with the oesophagus, or has low calcium levels in the blood should not take this medicine.

    It has been seen that ALENDRONATE SODIUM increases the risk of jaw bone problems (osteonecrosis), especially in persons with pre-existing dental problems or people treated with steroids, cancer, blood cell disorders, chemotherapy, or radiation.

    A person should take extra care of their dental hygiene while using ALENDRONATE SODIUM, and if they are going for any dental work (especially surgery), they should tell the dentist ahead of time that they are taking this medicine.

    Persons whose age is more than 35 years have low estrogen levels, females reaching menopause, too much consumption of alcohol, tobacco, or caffeine, use of glucocorticoids and lack of calcium and vitamin D in foods are some of the factors that can increase the risk of osteoporosis.

    If a person notices serious problems in the stomach or oesophagus, they should stop taking this medicine and report to the doctor immediately.

    ALENDRONATE SODIUM is part of a complete program that includes diet modifications, regular exercise, bone mineral density testing, and calcium and vitamin supplement intake. Follow all the guidelines given by the doctor very closely.

    A person should limit or quit smoking as it can reduce bone mineral density and increase the risks of fractures.

    ALENDRONATE SODIUM may cause side effects like stomach pain, constipation, nausea, gas, and diarrhoea. Most of these side effects of ALENDRONATE SODIUM do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

    Lying down after taking ALENDRONATE SODIUM may irritate the oesophagus and stomach. Therefore, do not lie down for at least 30 minutes after you take ALENDRONATE SODIUM. Sit or stand upright for at least 30 minutes after taking ALENDRONATE SODIUM.

    Yes, ALENDRONATE SODIUM may cause hair loss as a side effect. If you experience hair loss during treatment with ALENDRONATE SODIUM, please consult the doctor.

    ALENDRONATE SODIUM should be used in pregnant women only if prescribed by the doctor. Please consult the doctor if you are pregnant or planning for pregnancy.

    ALENDRONATE SODIUM may cause hair loss and tiredness. However, it does not cause cancer or an increase in blood pressure. Please consult the doctor if you experience any unusual symptoms while on treatment with ALENDRONATE SODIUM.

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    ALENDRONATE SODIUM

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